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“Safe & Effective”, Then and Now



by Dr Sam Bailey


Digging into the history of an infamous pharmaceutical scandal. It was said to be safe & effective. Sound familiar?


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  1. Thalidomide:
    https://en.wikipedia.org/wiki/Thalidomide ↩

  2. Chemie Grünenthal:
    https://en.wikipedia.org/wiki/Gr%C3%BCnenthal ↩

  3. “From the Holocaust to Thalidomide: A Nazi Legacy” - AHRP January 10, 2014:
    https://ahrp.org/from-the-holocaust-to-thalidomide-a-nazi-legacy/ ↩

  4. Martin Staemmler:
    https://cau.gelehrtenverzeichnis.de/person/d6d1cbfd-107c-ac94-8bd4-4d4c60af34df?lang=de ↩

  5. Thalidomide’s Secret Past: The Link with Nazi Germany:
    https://www.oncozine.com/thalidomides-secret-past-the-link-with-nazi-germany/ ↩

  6. Thalidomide Brands:
    https://web.archive.org/web/20140303080734/http://www.thalidomideuk.com/thalidomidebrands.htm ↩

  7. Drug discovery : a history - Sneader, 2005:
    https://archive.org/details/drugdiscoveryhis00snea/page/n379/mode/2up?q=thalidomide ↩

  8. The last German war secret - Herald Sun, June 27, 2011:
    https://web.archive.org/web/20120415072228/http://www.heraldsun.com.au/news/the-last-german-war-secret/story-e6frf7jo-1226082393923 ↩

  9. “GDR citizens slept without thalidomide”:
    https://www.nd-aktuell.de/artikel/120351.ddr-buerger-schliefen-ohne-contergan.html ↩

  10. Canadian Thalidomide Experience - 1963 Special Report:
    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1921912/pdf/canmedaj01021-0028.pdf ↩

  11. Dark Remedy - Stephens & Brynner, 2001:
    https://www.nejm.org/doi/full/10.1056/NEJM200107193450319 ↩

  12. Deadly Medicines and Organised Crime - Dr Peter Gøtzsche:
    https://www.amazon.com.au/Deadly-Medicines-Organised-Crime-Healthcare/dp/1846198844 ↩

  13. Summary of Cochrane’s show trial and illegal expulsion of Peter C Gøtzsche:
    https://www.deadlymedicines.dk/ ↩

  14. HPV vaccination to prevent cancer and pre-cancerous changes of the cervix - Cochrane 2018:
    https://www.cochrane.org/CD009069/GYNAECA_hpv-vaccination-prevent-cancer-and-pre-cancerous-changes-cervix ↩

  15. The Cochrane HPV vaccine review was incomplete and ignored important evidence of bias -
    https://ebm.bmj.com/content/ebmed/23/5/165.full.pdf ↩

  16. Virus Mania - 3rd English edition. ↩

  17. Daily Mail - 1 September 2012:
    https://www.dailymail.co.uk/news/article-2196689/Thalidomide-German-firm-invented-birth-defect-drug-apologises-time-50-years.html ↩

  18. A Detailed History and Timeline by Rosaleen Moriarty-Simmonds OBE:
    https://www.rms-consultancy.co.uk/personnel/thalidomide-detailed-history-and-timeline/ ↩

  19. GSK Hid Morning Sickness Drug's Birth Defect Risks: Suit:
    https://www.law360.com/articles/280573/gsk-hid-morning-sickness-drug-s-birth-defect-risks-suit ↩

  20. From the Holocaust to Thalidomide: A Nazi Legacy - Dr Judy Stone:
    https://blogs.scientificamerican.com/molecules-to-medicine/from-the-holocaust-to-thalidomide-a-nazi-legacy/ ↩

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